TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.
Identifieur interne : 000482 ( Main/Exploration ); précédent : 000481; suivant : 000483TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.
Auteurs : Bhawana Uprety [États-Unis] ; Amala Kaja [États-Unis] ; Sukesh R. Bhaumik [États-Unis]Source :
- Molecular and cellular biology [ 1098-5549 ] ; 2018.
Descripteurs français
- KwdFr :
- Activation de la transcription (MeSH), Adenosine triphosphatases (génétique), Adenosine triphosphatases (métabolisme), Facteur de transcription TFIID (génétique), Facteur de transcription TFIID (métabolisme), Gènes fongiques (MeSH), Histone acetyltransferases (génétique), Histone acetyltransferases (métabolisme), Modèles biologiques (MeSH), Mutation (MeSH), Proteasome endopeptidase complex (génétique), Proteasome endopeptidase complex (métabolisme), Protein-Serine-Threonine Kinases (génétique), Protein-Serine-Threonine Kinases (métabolisme), Protéines de Saccharomyces cerevisiae (génétique), Protéines de Saccharomyces cerevisiae (métabolisme), Protéines ribosomiques (génétique), Protéines ribosomiques (métabolisme), Régions promotrices (génétique) (MeSH), Régulation de l'expression des gènes fongiques (MeSH), Saccharomyces cerevisiae (génétique), Saccharomyces cerevisiae (métabolisme).
- MESH :
- génétique : Adenosine triphosphatases, Facteur de transcription TFIID, Histone acetyltransferases, Proteasome endopeptidase complex, Protein-Serine-Threonine Kinases, Protéines de Saccharomyces cerevisiae, Protéines ribosomiques, Saccharomyces cerevisiae.
- métabolisme : Adenosine triphosphatases, Facteur de transcription TFIID, Histone acetyltransferases, Proteasome endopeptidase complex, Protein-Serine-Threonine Kinases, Protéines de Saccharomyces cerevisiae, Protéines ribosomiques, Saccharomyces cerevisiae.
- Activation de la transcription, Gènes fongiques, Modèles biologiques, Mutation, Régions promotrices (génétique), Régulation de l'expression des gènes fongiques.
English descriptors
- KwdEn :
- Adenosine Triphosphatases (genetics), Adenosine Triphosphatases (metabolism), Gene Expression Regulation, Fungal (MeSH), Genes, Fungal (MeSH), Histone Acetyltransferases (genetics), Histone Acetyltransferases (metabolism), Models, Biological (MeSH), Mutation (MeSH), Promoter Regions, Genetic (MeSH), Proteasome Endopeptidase Complex (genetics), Proteasome Endopeptidase Complex (metabolism), Protein-Serine-Threonine Kinases (genetics), Protein-Serine-Threonine Kinases (metabolism), Ribosomal Proteins (genetics), Ribosomal Proteins (metabolism), Saccharomyces cerevisiae (genetics), Saccharomyces cerevisiae (metabolism), Saccharomyces cerevisiae Proteins (genetics), Saccharomyces cerevisiae Proteins (metabolism), Transcription Factor TFIID (genetics), Transcription Factor TFIID (metabolism), Transcriptional Activation (MeSH).
- MESH :
- chemical , genetics : Adenosine Triphosphatases, Histone Acetyltransferases, Proteasome Endopeptidase Complex, Protein-Serine-Threonine Kinases, Ribosomal Proteins, Saccharomyces cerevisiae Proteins, Transcription Factor TFIID.
- chemical , metabolism : Adenosine Triphosphatases, Histone Acetyltransferases, Proteasome Endopeptidase Complex, Protein-Serine-Threonine Kinases, Ribosomal Proteins, Saccharomyces cerevisiae Proteins, Transcription Factor TFIID.
- genetics : Saccharomyces cerevisiae.
- metabolism : Saccharomyces cerevisiae.
- Gene Expression Regulation, Fungal, Genes, Fungal, Models, Biological, Mutation, Promoter Regions, Genetic, Transcriptional Activation.
Abstract
TOR (target of rapamycin) has been previously implicated in transcriptional stimulation of the ribosomal protein (RP) genes via enhanced recruitment of NuA4 (nucleosome acetyltransferase of H4) to the promoters. However, it is not clearly understood how TOR enhances NuA4 recruitment to the promoters of the RP genes. Here we show that TOR facilitates the recruitment of the 19S proteasome subcomplex to the activator to enhance the targeting of NuA4 to the promoters of the RP genes. NuA4, in turn, promotes the recruitment of TFIID (transcription factor IID, composed of TATA box-binding protein [TBP] and a set of TBP-associated factors [TAFs]) and RNA polymerase II to the promoters of the RP genes to enhance transcriptional initiation. Therefore, our results demonstrate that TOR facilitates the recruitment of the 19S proteasome subcomplex to the promoters of the RP genes to promote the targeting of NuA4 for enhanced preinitiation complex (PIC) formation and consequently transcriptional initiation, hence illuminating TOR regulation of RP gene activation. Further, our results reveal that TOR differentially regulates PIC formation (and hence transcription) at the non-RP genes, thus demonstrating a complex regulation of gene activation by TOR.
DOI: 10.1128/MCB.00469-17
PubMed: 29712756
PubMed Central: PMC6024167
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.</title><author><name sortKey="Uprety, Bhawana" sort="Uprety, Bhawana" uniqKey="Uprety B" first="Bhawana" last="Uprety">Bhawana Uprety</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Kaja, Amala" sort="Kaja, Amala" uniqKey="Kaja A" first="Amala" last="Kaja">Amala Kaja</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bhaumik, Sukesh R" sort="Bhaumik, Sukesh R" uniqKey="Bhaumik S" first="Sukesh R" last="Bhaumik">Sukesh R. Bhaumik</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA sbhaumik@siumed.edu.</nlm:affiliation><country wicri:rule="url">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29712756</idno><idno type="pmid">29712756</idno><idno type="doi">10.1128/MCB.00469-17</idno><idno type="pmc">PMC6024167</idno><idno type="wicri:Area/Main/Corpus">000565</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000565</idno><idno type="wicri:Area/Main/Curation">000565</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000565</idno><idno type="wicri:Area/Main/Exploration">000565</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.</title><author><name sortKey="Uprety, Bhawana" sort="Uprety, Bhawana" uniqKey="Uprety B" first="Bhawana" last="Uprety">Bhawana Uprety</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Kaja, Amala" sort="Kaja, Amala" uniqKey="Kaja A" first="Amala" last="Kaja">Amala Kaja</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Bhaumik, Sukesh R" sort="Bhaumik, Sukesh R" uniqKey="Bhaumik S" first="Sukesh R" last="Bhaumik">Sukesh R. Bhaumik</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA sbhaumik@siumed.edu.</nlm:affiliation><country wicri:rule="url">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author></analytic><series><title level="j">Molecular and cellular biology</title><idno type="eISSN">1098-5549</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenosine Triphosphatases (genetics)</term><term>Adenosine Triphosphatases (metabolism)</term><term>Gene Expression Regulation, Fungal (MeSH)</term><term>Genes, Fungal (MeSH)</term><term>Histone Acetyltransferases (genetics)</term><term>Histone Acetyltransferases (metabolism)</term><term>Models, Biological (MeSH)</term><term>Mutation (MeSH)</term><term>Promoter Regions, Genetic (MeSH)</term><term>Proteasome Endopeptidase Complex (genetics)</term><term>Proteasome Endopeptidase Complex (metabolism)</term><term>Protein-Serine-Threonine Kinases (genetics)</term><term>Protein-Serine-Threonine Kinases (metabolism)</term><term>Ribosomal Proteins (genetics)</term><term>Ribosomal Proteins (metabolism)</term><term>Saccharomyces cerevisiae (genetics)</term><term>Saccharomyces cerevisiae (metabolism)</term><term>Saccharomyces cerevisiae Proteins (genetics)</term><term>Saccharomyces cerevisiae Proteins (metabolism)</term><term>Transcription Factor TFIID (genetics)</term><term>Transcription Factor TFIID (metabolism)</term><term>Transcriptional Activation (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activation de la transcription (MeSH)</term><term>Adenosine triphosphatases (génétique)</term><term>Adenosine triphosphatases (métabolisme)</term><term>Facteur de transcription TFIID (génétique)</term><term>Facteur de transcription TFIID (métabolisme)</term><term>Gènes fongiques (MeSH)</term><term>Histone acetyltransferases (génétique)</term><term>Histone acetyltransferases (métabolisme)</term><term>Modèles biologiques (MeSH)</term><term>Mutation (MeSH)</term><term>Proteasome endopeptidase complex (génétique)</term><term>Proteasome endopeptidase complex (métabolisme)</term><term>Protein-Serine-Threonine Kinases (génétique)</term><term>Protein-Serine-Threonine Kinases (métabolisme)</term><term>Protéines de Saccharomyces cerevisiae (génétique)</term><term>Protéines de Saccharomyces cerevisiae (métabolisme)</term><term>Protéines ribosomiques (génétique)</term><term>Protéines ribosomiques (métabolisme)</term><term>Régions promotrices (génétique) (MeSH)</term><term>Régulation de l'expression des gènes fongiques (MeSH)</term><term>Saccharomyces cerevisiae (génétique)</term><term>Saccharomyces cerevisiae (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Adenosine Triphosphatases</term><term>Histone Acetyltransferases</term><term>Proteasome Endopeptidase Complex</term><term>Protein-Serine-Threonine Kinases</term><term>Ribosomal Proteins</term><term>Saccharomyces cerevisiae Proteins</term><term>Transcription Factor TFIID</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Adenosine Triphosphatases</term><term>Histone Acetyltransferases</term><term>Proteasome Endopeptidase Complex</term><term>Protein-Serine-Threonine Kinases</term><term>Ribosomal Proteins</term><term>Saccharomyces cerevisiae Proteins</term><term>Transcription Factor TFIID</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Adenosine triphosphatases</term><term>Facteur de transcription TFIID</term><term>Histone acetyltransferases</term><term>Proteasome endopeptidase complex</term><term>Protein-Serine-Threonine Kinases</term><term>Protéines de Saccharomyces cerevisiae</term><term>Protéines ribosomiques</term><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Adenosine triphosphatases</term><term>Facteur de transcription TFIID</term><term>Histone acetyltransferases</term><term>Proteasome endopeptidase complex</term><term>Protein-Serine-Threonine Kinases</term><term>Protéines de Saccharomyces cerevisiae</term><term>Protéines ribosomiques</term><term>Saccharomyces cerevisiae</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Gene Expression Regulation, Fungal</term><term>Genes, Fungal</term><term>Models, Biological</term><term>Mutation</term><term>Promoter Regions, Genetic</term><term>Transcriptional Activation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Activation de la transcription</term><term>Gènes fongiques</term><term>Modèles biologiques</term><term>Mutation</term><term>Régions promotrices (génétique)</term><term>Régulation de l'expression des gènes fongiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">TOR (target of rapamycin) has been previously implicated in transcriptional stimulation of the ribosomal protein (RP) genes via enhanced recruitment of NuA4 (nucleosome acetyltransferase of H4) to the promoters. However, it is not clearly understood how TOR enhances NuA4 recruitment to the promoters of the RP genes. Here we show that TOR facilitates the recruitment of the 19S proteasome subcomplex to the activator to enhance the targeting of NuA4 to the promoters of the RP genes. NuA4, in turn, promotes the recruitment of TFIID (transcription factor IID, composed of TATA box-binding protein [TBP] and a set of TBP-associated factors [TAFs]) and RNA polymerase II to the promoters of the RP genes to enhance transcriptional initiation. Therefore, our results demonstrate that TOR facilitates the recruitment of the 19S proteasome subcomplex to the promoters of the RP genes to promote the targeting of NuA4 for enhanced preinitiation complex (PIC) formation and consequently transcriptional initiation, hence illuminating TOR regulation of RP gene activation. Further, our results reveal that TOR differentially regulates PIC formation (and hence transcription) at the non-RP genes, thus demonstrating a complex regulation of gene activation by TOR.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29712756</PMID><DateCompleted><Year>2019</Year><Month>06</Month><Day>17</Day></DateCompleted><DateRevised><Year>2019</Year><Month>06</Month><Day>17</Day></DateRevised><Article PubModel="Electronic-Print"><Journal><ISSN IssnType="Electronic">1098-5549</ISSN><JournalIssue CitedMedium="Internet"><Volume>38</Volume><Issue>14</Issue><PubDate><Year>2018</Year><Month>07</Month><Day>15</Day></PubDate></JournalIssue><Title>Molecular and cellular biology</Title><ISOAbbreviation>Mol Cell Biol</ISOAbbreviation></Journal><ArticleTitle>TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">e00469-17</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1128/MCB.00469-17</ELocationID><Abstract><AbstractText>TOR (target of rapamycin) has been previously implicated in transcriptional stimulation of the ribosomal protein (RP) genes via enhanced recruitment of NuA4 (nucleosome acetyltransferase of H4) to the promoters. However, it is not clearly understood how TOR enhances NuA4 recruitment to the promoters of the RP genes. Here we show that TOR facilitates the recruitment of the 19S proteasome subcomplex to the activator to enhance the targeting of NuA4 to the promoters of the RP genes. NuA4, in turn, promotes the recruitment of TFIID (transcription factor IID, composed of TATA box-binding protein [TBP] and a set of TBP-associated factors [TAFs]) and RNA polymerase II to the promoters of the RP genes to enhance transcriptional initiation. Therefore, our results demonstrate that TOR facilitates the recruitment of the 19S proteasome subcomplex to the promoters of the RP genes to promote the targeting of NuA4 for enhanced preinitiation complex (PIC) formation and consequently transcriptional initiation, hence illuminating TOR regulation of RP gene activation. Further, our results reveal that TOR differentially regulates PIC formation (and hence transcription) at the non-RP genes, thus demonstrating a complex regulation of gene activation by TOR.</AbstractText><CopyrightInformation>Copyright © 2018 American Society for Microbiology.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Uprety</LastName><ForeName>Bhawana</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kaja</LastName><ForeName>Amala</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhaumik</LastName><ForeName>Sukesh R</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA sbhaumik@siumed.edu.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R15 GM088798</GrantID><Acronym>GM</Acronym><Agency>NIGMS NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2018</Year><Month>06</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mol Cell Biol</MedlineTA><NlmUniqueID>8109087</NlmUniqueID><ISSNLinking>0270-7306</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012269">Ribosomal Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D029701">Saccharomyces cerevisiae Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D035362">Transcription Factor TFIID</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.3.1.48</RegistryNumber><NameOfSubstance UI="D051548">Histone Acetyltransferases</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.3.1.48</RegistryNumber><NameOfSubstance UI="C504740">NuA4 protein, S cerevisiae</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber><NameOfSubstance UI="D017346">Protein-Serine-Threonine Kinases</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber><NameOfSubstance UI="C500749">target of rapamycin protein, S cerevisiae</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.25.1</RegistryNumber><NameOfSubstance UI="D046988">Proteasome Endopeptidase Complex</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.6.1.-</RegistryNumber><NameOfSubstance UI="D000251">Adenosine Triphosphatases</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.6.1.-</RegistryNumber><NameOfSubstance UI="C103015">RPT4 protein, S cerevisiae</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000251" MajorTopicYN="N">Adenosine Triphosphatases</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015966" MajorTopicYN="N">Gene Expression Regulation, Fungal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005800" MajorTopicYN="N">Genes, Fungal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D051548" MajorTopicYN="N">Histone Acetyltransferases</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008954" MajorTopicYN="N">Models, Biological</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009154" MajorTopicYN="N">Mutation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011401" MajorTopicYN="N">Promoter Regions, Genetic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D046988" MajorTopicYN="N">Proteasome Endopeptidase Complex</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017346" MajorTopicYN="N">Protein-Serine-Threonine Kinases</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012269" MajorTopicYN="N">Ribosomal Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012441" MajorTopicYN="N">Saccharomyces cerevisiae</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D029701" MajorTopicYN="N">Saccharomyces cerevisiae Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D035362" MajorTopicYN="N">Transcription Factor TFIID</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015533" MajorTopicYN="N">Transcriptional Activation</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">19S proteasome subcomplex</Keyword><Keyword MajorTopicYN="Y">NuA4</Keyword><Keyword MajorTopicYN="Y">RNA polymerase II</Keyword><Keyword MajorTopicYN="Y">TBP</Keyword><Keyword MajorTopicYN="Y">TOR</Keyword><Keyword MajorTopicYN="Y">transcription</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>09</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>04</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>5</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>6</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>5</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29712756</ArticleId><ArticleId IdType="pii">MCB.00469-17</ArticleId><ArticleId IdType="doi">10.1128/MCB.00469-17</ArticleId><ArticleId IdType="pmc">PMC6024167</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Genes Dev. 2004 Feb 1;18(3):333-43</Citation><ArticleIdList><ArticleId IdType="pubmed">14871930</ArticleId></ArticleIdList></Reference><Reference><Citation>FEMS Microbiol Lett. 2007 Aug;273(2):239-43</Citation><ArticleIdList><ArticleId IdType="pubmed">17573937</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2011 Feb;1809(2):97-108</Citation><ArticleIdList><ArticleId IdType="pubmed">20800707</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 2006 Feb;172(2):1369-72</Citation><ArticleIdList><ArticleId IdType="pubmed">16322523</ArticleId></ArticleIdList></Reference><Reference><Citation>BMB Rep. 2016 Sep;49(9):459-73</Citation><ArticleIdList><ArticleId IdType="pubmed">27312603</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Biol. 2002 Jul 23;12(14):1240-4</Citation><ArticleIdList><ArticleId IdType="pubmed">12176335</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2009 Dec;29(24):6473-87</Citation><ArticleIdList><ArticleId IdType="pubmed">19822662</ArticleId></ArticleIdList></Reference><Reference><Citation>Chem Biol. 2004 Mar;11(3):295-9</Citation><ArticleIdList><ArticleId IdType="pubmed">15123258</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 1999 Jun 10;399(6736):605-9</Citation><ArticleIdList><ArticleId IdType="pubmed">10376604</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2011 Feb;1809(2):88-96</Citation><ArticleIdList><ArticleId IdType="pubmed">20723625</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2011 Mar 2;30(5):859-72</Citation><ArticleIdList><ArticleId IdType="pubmed">21183953</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2010 Mar;38(5):1461-77</Citation><ArticleIdList><ArticleId IdType="pubmed">20007604</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2001 Mar 30;276(13):9825-31</Citation><ArticleIdList><ArticleId IdType="pubmed">11152478</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2000 May 26;288(5470):1422-5</Citation><ArticleIdList><ArticleId IdType="pubmed">10827952</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2002 Aug;22(15):5575-84</Citation><ArticleIdList><ArticleId IdType="pubmed">12101249</ArticleId></ArticleIdList></Reference><Reference><Citation>Crit Rev Biochem Mol Biol. 2008 Nov-Dec;43(6):419-33</Citation><ArticleIdList><ArticleId IdType="pubmed">19058045</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2010 Feb 05;5(2):e9084</Citation><ArticleIdList><ArticleId IdType="pubmed">20140209</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2004 Dec 29;119(7):969-79</Citation><ArticleIdList><ArticleId IdType="pubmed">15620355</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2003 Jul 1;22(13):3395-402</Citation><ArticleIdList><ArticleId IdType="pubmed">12840001</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Cell. 2013 Dec;24(23):3697-709</Citation><ArticleIdList><ArticleId IdType="pubmed">24088570</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2007 Aug;27(15):5327-35</Citation><ArticleIdList><ArticleId IdType="pubmed">17526728</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 1991 Mar 22;64(6):1135-43</Citation><ArticleIdList><ArticleId IdType="pubmed">2004420</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2011 Feb;31(4):818-31</Citation><ArticleIdList><ArticleId IdType="pubmed">21149579</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2003 Feb;11(2):365-76</Citation><ArticleIdList><ArticleId IdType="pubmed">12620225</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 2004 Oct 15;18(20):2491-505</Citation><ArticleIdList><ArticleId IdType="pubmed">15466158</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2009 Dec 18;284(51):35714-24</Citation><ArticleIdList><ArticleId IdType="pubmed">19843524</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2008 Mar 14;283(11):6897-905</Citation><ArticleIdList><ArticleId IdType="pubmed">18195014</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Apr;40(8):3348-63</Citation><ArticleIdList><ArticleId IdType="pubmed">22199252</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2005 Nov 4;123(3):423-36</Citation><ArticleIdList><ArticleId IdType="pubmed">16269334</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2004 Feb 27;13(4):573-85</Citation><ArticleIdList><ArticleId IdType="pubmed">14992726</ArticleId></ArticleIdList></Reference><Reference><Citation>Oncogene. 2006 Oct 16;25(48):6384-91</Citation><ArticleIdList><ArticleId IdType="pubmed">17041624</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods Enzymol. 2003;370:445-54</Citation><ArticleIdList><ArticleId IdType="pubmed">14712666</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 2001 May 4;496(1):31-5</Citation><ArticleIdList><ArticleId IdType="pubmed">11343701</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 2018 Jan;208(1):191-205</Citation><ArticleIdList><ArticleId IdType="pubmed">29141908</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2000 Dec;6(6):1297-307</Citation><ArticleIdList><ArticleId IdType="pubmed">11163204</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2004 Dec 23;432(7020):1058-61</Citation><ArticleIdList><ArticleId IdType="pubmed">15616569</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2006 May;26(9):3339-52</Citation><ArticleIdList><ArticleId IdType="pubmed">16611979</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2015 Sep 1;35(17):2947-64</Citation><ArticleIdList><ArticleId IdType="pubmed">26100014</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cancer. 2009 Sep 24;8:75</Citation><ArticleIdList><ArticleId IdType="pubmed">19778445</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2003 Jan;23(2):629-35</Citation><ArticleIdList><ArticleId IdType="pubmed">12509460</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 2014 Jan;196(1):161-76</Citation><ArticleIdList><ArticleId IdType="pubmed">24172134</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2003 Feb;11(2):353-63</Citation><ArticleIdList><ArticleId IdType="pubmed">12620224</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 2014 Aug 12;426(16):2928-2941</Citation><ArticleIdList><ArticleId IdType="pubmed">24911582</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2002 Apr;9(4):823-33</Citation><ArticleIdList><ArticleId IdType="pubmed">11983173</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14866-70</Citation><ArticleIdList><ArticleId IdType="pubmed">10611304</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2017 Jun 29;12(6):e0179893</Citation><ArticleIdList><ArticleId IdType="pubmed">28662109</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 1999 Apr;19(4):2515-26</Citation><ArticleIdList><ArticleId IdType="pubmed">10082517</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2012 Jan;1825(1):64-76</Citation><ArticleIdList><ArticleId IdType="pubmed">22037302</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Mar;40(5):1969-83</Citation><ArticleIdList><ArticleId IdType="pubmed">22086954</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 May 21;285(21):15966-77</Citation><ArticleIdList><ArticleId IdType="pubmed">20332092</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochemistry. 2012 Jul 31;51(30):5873-5</Citation><ArticleIdList><ArticleId IdType="pubmed">22794311</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 1999 Dec 15;13(24):3271-9</Citation><ArticleIdList><ArticleId IdType="pubmed">10617575</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Proteomics. 2014 Aug;13(8):1979-92</Citation><ArticleIdList><ArticleId IdType="pubmed">24961812</ArticleId></ArticleIdList></Reference><Reference><Citation>OMICS. 2010 Dec;14(6):629-38</Citation><ArticleIdList><ArticleId IdType="pubmed">20863251</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2009 May;29(10):2876-88</Citation><ArticleIdList><ArticleId IdType="pubmed">19273591</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2004 Dec 23;432(7020):1054-8</Citation><ArticleIdList><ArticleId IdType="pubmed">15616568</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Sci. 2013 Apr 15;126(Pt 8):1713-9</Citation><ArticleIdList><ArticleId IdType="pubmed">23641065</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Biochem Sci. 1999 Nov;24(11):437-40</Citation><ArticleIdList><ArticleId IdType="pubmed">10542411</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2002 Nov;22(21):7365-71</Citation><ArticleIdList><ArticleId IdType="pubmed">12370284</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2000 May 19;288(5469):1242-4</Citation><ArticleIdList><ArticleId IdType="pubmed">10817999</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2005 Feb 9;24(3):533-42</Citation><ArticleIdList><ArticleId IdType="pubmed">15692568</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 2000 Apr 15;14(8):951-62</Citation><ArticleIdList><ArticleId IdType="pubmed">10783167</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2007 Jan;27(1):297-311</Citation><ArticleIdList><ArticleId IdType="pubmed">17074814</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Struct Biol. 2003 Dec;10(12):1039-47</Citation><ArticleIdList><ArticleId IdType="pubmed">14608375</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2000 Oct 13;103(2):253-62</Citation><ArticleIdList><ArticleId IdType="pubmed">11057898</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Biol. 2013 Sep;33(18):3549-67</Citation><ArticleIdList><ArticleId IdType="pubmed">23836882</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15201-6</Citation><ArticleIdList><ArticleId IdType="pubmed">21876130</ArticleId></ArticleIdList></Reference><Reference><Citation>Yeast. 1998 Jul;14(10):953-61</Citation><ArticleIdList><ArticleId IdType="pubmed">9717241</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Cell. 1999 Apr;10(4):987-1000</Citation><ArticleIdList><ArticleId IdType="pubmed">10198052</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 Oct 1;285(40):30472-9</Citation><ArticleIdList><ArticleId IdType="pubmed">20668333</ArticleId></ArticleIdList></Reference><Reference><Citation>RNA. 2014 Feb;20(2):133-42</Citation><ArticleIdList><ArticleId IdType="pubmed">24327750</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 May 14;285(20):15489-99</Citation><ArticleIdList><ArticleId IdType="pubmed">20189987</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(8):e23159</Citation><ArticleIdList><ArticleId IdType="pubmed">21887235</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2013 Apr 5;288(14):9619-33</Citation><ArticleIdList><ArticleId IdType="pubmed">23417674</ArticleId></ArticleIdList></Reference><Reference><Citation>Proteomics. 2010 Aug;10(15):2769-79</Citation><ArticleIdList><ArticleId IdType="pubmed">20486117</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2014 Sep;42(15):9892-907</Citation><ArticleIdList><ArticleId IdType="pubmed">25114048</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Genomics. 2009 May;10(3):198-205</Citation><ArticleIdList><ArticleId IdType="pubmed">19881913</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Illinois</li></region></list><tree><country name="États-Unis"><region name="Illinois"><name sortKey="Uprety, Bhawana" sort="Uprety, Bhawana" uniqKey="Uprety B" first="Bhawana" last="Uprety">Bhawana Uprety</name></region><name sortKey="Bhaumik, Sukesh R" sort="Bhaumik, Sukesh R" uniqKey="Bhaumik S" first="Sukesh R" last="Bhaumik">Sukesh R. Bhaumik</name><name sortKey="Kaja, Amala" sort="Kaja, Amala" uniqKey="Kaja A" first="Amala" last="Kaja">Amala Kaja</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/RapamycinFungusV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000482 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000482 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= RapamycinFungusV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:29712756
|texte= TOR Facilitates the Targeting of the 19S Proteasome Subcomplex To Enhance Transcription Complex Assembly at the Promoters of the Ribosomal Protein Genes.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:29712756" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a RapamycinFungusV1
| This area was generated with Dilib version V0.6.38. |  |